Monitoring patterned enzymatic polymerization on DNA origami at single-molecule level.
نویسندگان
چکیده
DNA origami has been used to orchestrate reactions with nano-precision using a variety of biomolecules. Here, the dynamics of albumin-assisted, localized single-molecule DNA polymerization by terminal deoxynucleotidyl transferase on a 2D DNA origami are monitored using AFM in liquid. Direct visualization of the surface activity revealed the mechanics of growth.
منابع مشابه
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ورودعنوان ژورنال:
- Nanoscale
دوره 7 25 شماره
صفحات -
تاریخ انتشار 2015